Stomach Carcinoma
|
0.100 |
GeneticVariation
|
disease |
BEFREE |
Predictive Value of Two Polymorphisms of ERCC2, rs13181 and rs1799793, in Clinical Outcomes of Chemotherapy in Gastric Cancer Patients: A Meta-Analysis.
|
30581498 |
2018 |
Stomach Carcinoma
|
0.100 |
GeneticVariation
|
disease |
BEFREE |
However, we did not find any association of polymorphism of XRCC1 Arg399Gln (OR = 1.56; 95% CI: 0.32-7.82) and XPD Lys751Gln (OR = 0.46; CI: 0.10-2.19) with GC risk in the study population.
|
30225185 |
2018 |
Stomach Carcinoma
|
0.100 |
GeneticVariation
|
disease |
BEFREE |
However, we found no association between ERCC1 rs11615, ERCC2 rs13181, and ERCC2 rs1799793 and overall survival of gastric cancer.
|
27173253 |
2016 |
Stomach Carcinoma
|
0.100 |
GeneticVariation
|
disease |
BEFREE |
In conclusion, ERCC1 rs11615, rs2298881 and ERCC2 rs1799793 polymorphism play an important role in the treatment outcome of gastric cancer.
|
26097599 |
2015 |
Stomach Carcinoma
|
0.100 |
GeneticVariation
|
disease |
BEFREE |
In conclusion, our results suggest that ERCC1 rs11615, ERCC2 rs1799793, and NBN rs1805794 polymorphisms in the DNA repair pathways may influence the response to chemotherapy and OS of gastric cancer.
|
25542228 |
2015 |
Stomach Carcinoma
|
0.100 |
GeneticVariation
|
disease |
BEFREE |
Prognostic value of ERCC1 and ERCC2 gene polymorphisms in patients with gastric cancer receiving platinum-based chemotherapy.
|
26823845 |
2015 |
Stomach Carcinoma
|
0.100 |
GeneticVariation
|
disease |
BEFREE |
In conclusion, our finding suggests that ERCC1 rs3212986 and ERCC2 rs13181 gene polymorphism could influence the response to chemotherapy and clinical outcome of gastric cancer.
|
26191265 |
2015 |
Stomach Carcinoma
|
0.100 |
GeneticVariation
|
disease |
BEFREE |
We performed a study to investigate the role of ERCC1 (rs11615, rs2298881, and rs3212986) and ERCC2 (rs13181, rs238406, and rs1799793) polymorphisms in the prognosis of gastric cancer.
|
26782397 |
2015 |
Stomach Carcinoma
|
0.100 |
GeneticVariation
|
disease |
BEFREE |
We investigate whether three common polymorphisms in ERCC1 and ERCC2 are predictor factors for the chemotherapy response, as well as the clinic outcome of patients with gastric cancer.
|
26681216 |
2015 |
Stomach Carcinoma
|
0.100 |
GeneticVariation
|
disease |
BEFREE |
This meta-analysis aimed to obtain a comprehensive and reliable assessment of the relationships between XRCC1 Arg399Gln and XPD Lys751Gln polymorphisms and the clinical outcomes of gastric cancer (GC) patients treated with oxaliplatin-based chemotherapy.
|
24590266 |
2014 |
Stomach Carcinoma
|
0.100 |
GeneticVariation
|
disease |
BEFREE |
ERCC1 and ERCC2 variants predict survival in gastric cancer patients.
|
24023723 |
2013 |
Stomach Carcinoma
|
0.100 |
GeneticVariation
|
disease |
BEFREE |
We conclude that ERCC2 rs13181 polymorphism could play different roles in the overall survival of gastric cancer.
|
23680703 |
2013 |
Stomach Carcinoma
|
0.100 |
GeneticVariation
|
disease |
BEFREE |
The current study was to evaluate the association between genetic polymorphisms, including associated haplotypes of xeroderma pigmentosum complementary group D (XPD), and individual susceptibility to gastric cancer.
|
20842450 |
2011 |
Stomach Carcinoma
|
0.100 |
GeneticVariation
|
disease |
BEFREE |
For ERCC2 Asp312Asn polymorphism, significantly elevated GC risk was associated with Asn/Asn genotype (AA vs. GG + GA: OR = 1.36, 95%CI = 1.04-1.77, P = 0.02).
|
20981556 |
2011 |
Stomach Carcinoma
|
0.100 |
GeneticVariation
|
disease |
BEFREE |
Polymorphic variants of base excision repair (APE1-D148E, XRCC1-R194W, XRCC1-R399Q and OGG1-S326C), nucleotide excision repair (XPC-PAT, XPA-23G>A, ERCC1-19007T>C and XPD-L751Q), recombination (XRCC3-T241M) and alkylation damage reversal (MGMT-L84F) were tested for their potential role in the development of GC by using logistic regression models.
|
20817763 |
2010 |
Stomach Carcinoma
|
0.100 |
Biomarker
|
disease |
BEFREE |
Our study supports a role of ERCC2 in non-cardial GC but not in cardial cancer.
|
18641418 |
2008 |